Endocrine Abstracts

Oxidative stress plays an important role in hyperthyroidism-induced tissue damage. We aimed to determine whether radioiodine therapy has benefit effect on the oxidant and antioxidant status in patients with Graves’ Disease.Material and methods: We studied 30 patients with Graves’ disease, aged 18–48 years. 12 normal adult volunteers were studied as control group. All the patients were treated unsuccessfully by antithyroid drugs. The effect...

A young woman aged 23 years, with non-toxic goiter was treated in our Department. Serum levels of FT4, FT3 and TSH were within normal range, high resolution ultrasonography show very large glands (60 ml), with large nodule in left lobe and smaller one in the right lobe. Malignancy was ruled out by ultrasound-guided fine-needle aspiration biopsy. Thyroid radioiodine scintigraphy showed homogenous and diffuse uptake in the right lobe, with very low uptake i...

Oxidative stress plays an important role in hyperthyroidism induced – tissue damage.We aimed to determine whether radioiodine therapy (RIT) has benefit effect on the oxidant and antioxidant status in subclinical hyperthyroidism.Material and methods: We studied 40 patients with untreated subclinical hyperthyroidism, (33 female, 7 male), aged 23–78 years; 14 patients with multinodular goitre, and 25 patients with solitary a...

There is no consensus regarding the optimum treatment of benign non-toxic goitre. Randomised studies have shown that levothyroxine has poor evidence of efficacy and is inferior to radioiodine therapy regarding goitre reduction.The aim of our study was to assess the efficacy of radioiodine therapy (RIT) to reduce thyroid volume with minimal risk of hypothyroidism in patients with non-toxic nodular goitre.Material and methods: During...

Oxidative stress plays an important role in hyperthyroidism-induced tissue damage.We aimed to determine whether radioiodine therapy has benefit effect on the oxidant and antioxidant status in patients with toxic nodular goitre.Material and methods: We studied 40 patients with toxic nodular goitre, (31 female, 9 male), aged 21–65 years. 12 normal adult volunteers (age and sex-matched) were studied as control group. All the pati...